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The WHI estrogen-plus-progestin substudy demonstrated an increased risk of invasive breast cancer.
Estrace 2 mg tablets contain tartrazine which may cause allergic-type reactionsincluding bronchial asthmain certain susceptible individualsAlthough the overall incidence of FD&C Yellow No5tartrazinesensitivity in the general population is lowit is frequently seen in patients who also have aspirin hypersensitivity.
Retinal vascular thrombosis has been reported in patients receiving estrogensDiscontinue medication pending examination if there is sudden partial or complete loss of visionor a sudden onset of proptosisdiplopia or migraineIf examination reveals papilledema or retinal vascular lesionsestrogens should be permanently discontinued.
Inactive IngredientsColloidal silicon dioxidecorn starchdibasic calcium phosphatelactose monohydratemagnesium stearateand sodium starch glycolateIn additionthe 1 mg also contains FD&C blue no1 aluminum lake and D&C red no27 aluminum lakeThe 2 mg also contains FD&C blue no1 aluminum lake and FD&C yellow no5tartrazinealuminum lake.
When prescribing solely for the prevention of postmenopausal osteoporosistherapy should be considered only for women at significant risk of osteoporosis and for whom non-estrogen medications are not considered to be appropriate.
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